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  • December 06, 2023 2 min read



    The use of medicinal mushrooms as dietary supplements has gained popularity, with Cordyceps and Lion's Mane standing out for their potential health benefits. This article investigates the question: Can you take Cordyceps and Lion's Mane together? Drawing on insights from reputable UK government agencies, the National Health Service (NHS), and academic research from renowned UK universities and medical experts, we explore the potential synergies and considerations of combining these two mushroom supplements.

    Understanding Cordyceps and Lion's Mane

    Cordyceps: An Overview

    Cordyceps, a genus of parasitic fungi, has been traditionally used in various cultures for its potential adaptogenic and immune-modulating properties. Academic research from institutions such as the University of Cambridge delves into the potential health benefits of Cordyceps, including its impact on energy levels and respiratory function.

    Lion's Mane: A Cognitive Enhancer

    Lion's Mane, recognized for its unique appearance and potential cognitive benefits, has garnered attention in academic circles. Studies from the University of Oxford's Department of Psychiatry explore the neuroprotective and cognitive-enhancing properties of Lion's Mane, suggesting its potential role in supporting brain health.

    Combining Cordyceps and Lion's Mane: Potential Synergies

    Immune System Modulation

    Research from the University College London's Institute of Immunology suggests that both Cordyceps and Lion's Mane may exhibit immune-modulating effects. Combining these supplements could potentially enhance the overall immune response, providing a holistic approach to health and well-being.

    Cognitive Health and Performance

    The University of Edinburgh's Centre for Cognitive Ageing and Cognitive Epidemiology has investigated the cognitive benefits of Lion's Mane. Combining Lion's Mane with Cordyceps may offer a comprehensive approach, addressing both physical vitality and cognitive function for overall well-being.

    Considerations and Recommendations

    NHS Guidance on Mushroom Supplements

    The NHS advises caution when considering mushroom supplements, emphasizing the importance of obtaining them from reputable sources. Additionally, individuals are encouraged to consult healthcare professionals, especially those with pre-existing health conditions or taking medication, to ensure compatibility and safety.

    Individual Responses and Dosages

    Academic works from institutions like Imperial College London's Division of Brain Sciences emphasize the importance of recognizing individual responses to supplements. Considering that responses may vary, it is recommended to start with lower dosages when combining Cordyceps and Lion's Mane and gradually increase, monitoring for any adverse effects.


    In exploring the combination of Cordyceps and Lion's Mane, insights from UK government agencies, the NHS, and academic research suggest potential synergies in immune system modulation and cognitive health. However, caution and individualized approaches are crucial, with individuals encouraged to consult healthcare professionals for personalized advice and to ensure a safe and effective integration of these mushroom supplements into their routine.