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  • October 27, 2023 2 min read


    Mushroom supplements are celebrated for their diverse health benefits, and many individuals seek to incorporate them into their daily routines. However, the prospect of experiencing fatigue as a side effect can raise questions about their safety and suitability.

    Cognitive-Enhancing Mushrooms and Fatigue

    Lion's Mane (Hericium erinaceus)

    Lion's Mane is known for its potential cognitive-enhancing properties. While some individuals report improved focus and mental clarity with Lion's Mane, others may experience increased alertness, potentially affecting sleep patterns if taken close to bedtime.

    Cordyceps (Ophiocordyceps sinensis)

    Cordyceps is valued for its adaptogenic and energy-boosting qualities. While it can improve endurance and reduce fatigue in some individuals, it may lead to heightened alertness, which, when taken in the evening, could disrupt sleep.

    Reishi (Ganoderma lucidum) and Relaxation

    Reishi, on the other hand, is often associated with relaxation and stress reduction. It contains compounds that may help individuals unwind and achieve better sleep quality. In this context, Reishi could have a positive impact on fatigue by promoting better rest.

    Consultation with Healthcare Professionals

    Individual responses to mushroom supplements can vary, and the timing of supplementation may play a crucial role in whether they contribute to alertness or relaxation. To address concerns about potential fatigue, it is advisable to consult with healthcare professionals who can provide personalized guidance based on individual health conditions and objectives.

    Regulatory Oversight in the UK

    Government Agencies

    In the UK, the Food Standards Agency (FSA) and the Medicines and Healthcare products Regulatory Agency (MHRA) regulate dietary supplements, including mushroom supplements. Their oversight ensures that products meet established criteria for safety and quality.

    Quality and Dosage Considerations

    The quality and dosage of mushroom supplements are significant factors influencing their effects. Choosing reputable manufacturers and adhering to recommended dosages is essential to maximize the potential benefits and minimize adverse effects.


    The relationship between mushroom supplements and fatigue is not one-size-fits-all. The impact of these supplements on energy levels and alertness depends on the specific mushroom, the timing of consumption, and individual responses.

    Cognitive-enhancing mushrooms like Lion's Mane and Cordyceps may promote alertness and heightened energy levels, while relaxation-promoting mushrooms like Reishi may help reduce stress and improve sleep quality, potentially mitigating fatigue. Consulting with healthcare professionals, adhering to high-quality supplements, and considering the timing of consumption are essential steps in achieving the desired effects and minimizing any potential side effects, including fatigue.