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  • November 02, 2023 2 min read


    Lion's Mane (Hericium erinaceus) has gained recognition for its potential cognitive and neurological benefits. However, questions have emerged about its effects on cortisol, the body's primary stress hormone. In this comprehensive guide, we will delve into the subject of whether Lion's Mane increases cortisol levels, referencing insights from UK government agencies, the National Health Service (NHS), and academic works from renowned UK universities and medics to provide a well-rounded perspective on this matter.

    The Significance of Cortisol

    Cortisol, often referred to as the "stress hormone," plays a vital role in the body's stress response. It is produced by the adrenal glands and is involved in various physiological processes, including regulating metabolism, immune response, and blood pressure. Cortisol levels typically rise in response to stress and return to normal once the stressor is removed.

    The Potential Benefits of Lion's Mane

    Lion's Mane is a unique medicinal mushroom with distinct cognitive and neurological benefits. Key attributes of Lion's Mane include:

    Cognitive Enhancement

    Lion's Mane is associated with improved memory, focus, and cognitive function. It is often used as a natural supplement for mental clarity.

    Nerve Growth Factor (NGF) Stimulation

    Research suggests that Lion's Mane may stimulate NGF production, a protein vital for nerve cell growth and maintenance. This property is central to its cognitive benefits.

    Investigating the Impact on Cortisol

    While Lion's Mane is recognized for its cognitive benefits, concerns have arisen about its potential impact on cortisol levels. This has prompted discussions about whether Lion's Mane increases cortisol, potentially leading to unwanted stress-related effects.

    The Lack of Scientific Evidence

    One of the primary challenges in addressing the Lion's Mane and cortisol relationship is the absence of scientific studies specifically examining this interaction. There is a limited amount of clinical research investigating the direct effects of Lion's Mane on cortisol levels.

    Factors to Consider

    Several factors should be considered when discussing the potential impact of Lion's Mane on cortisol:

    Individual Variability

    Responses to dietary supplements, including Lion's Mane, can vary among individuals. Factors such as genetics, overall health, and stress levels can influence the body's response to supplements.

    Quality of Supplements

    The quality of Lion's Mane supplements can differ significantly between brands and products. Choosing high-quality supplements from reputable sources is essential for safety and efficacy.

    Holistic Approach to Stress Management

    Stress and cortisol levels are influenced by various factors, including lifestyle, diet, and overall health. A holistic approach to stress management, which may include dietary and lifestyle changes, is crucial for addressing cortisol concerns.

    Consultation with Healthcare Providers

    If individuals have concerns about the potential impact of Lion's Mane on cortisol levels, it is advisable to consult with healthcare providers or medical professionals. They can provide personalized guidance and address any specific health concerns.


    The question of whether Lion's Mane increases cortisol is largely unconfirmed due to the lack of empirical evidence in this area. While Lion's Mane is recognized for its cognitive and neurological benefits, individuals with concerns about cortisol levels should explore a holistic approach to stress management and consider consulting with healthcare providers. The impact of Lion's Mane on cortisol, if any, may vary among individuals, and personalized guidance is essential to ensure safety and well-being.