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  • December 05, 2023 2 min read



    Lion's Mane mushroom (Hericium erinaceus) has garnered attention for its potential cognitive benefits, prompting questions about its impact on cortisol levels. In this article, we delve into the available academic works from distinguished UK universities, alongside guidance from UK government agencies and the National Health Service (NHS), to explore whether Lion's Mane has any discernible effect on cortisol.

    Understanding Cortisol

    Cortisol, commonly known as the "stress hormone," plays a vital role in the body's stress response and various physiological functions. Maintaining an appropriate balance is crucial for overall health, prompting interest in how dietary supplements, such as Lion's Mane, may influence cortisol levels.

    The Biochemistry of Lion's Mane

    Academic studies from leading UK universities have investigated the bioactive compounds in Lion's Mane and their potential effects on various physiological processes. While there is evidence to suggest that Lion's Mane may impact neurotrophic factors, there is limited direct research on its interaction with cortisol. This lack of specific studies underscores the need for caution and further exploration.

    Insights from UK Government Agencies

    The UK government, through its agencies, provides general guidelines on nutrition and dietary supplements. While there is no explicit mention of Lion's Mane in official recommendations, individuals are advised to approach supplements with care and seek advice from healthcare professionals. This caution is especially pertinent when considering potential effects on hormones, including cortisol.

    NHS Perspective on Lion's Mane and Cortisol

    The NHS, as a reliable source of healthcare information in the UK, emphasizes the importance of evidence-based practices. While Lion's Mane is not specifically discussed on the NHS website concerning cortisol levels, it highlights the significance of maintaining a balanced and varied diet. Individuals considering Lion's Mane supplements are encouraged to prioritize overall well-being and consult healthcare professionals.

    Limited Evidence on Lion's Mane and Cortisol

    Academic works from the UK have explored the neuroprotective and cognitive benefits of Lion's Mane but provide limited information on its direct influence on cortisol levels. The scientific community acknowledges the need for more targeted research to understand the specific interactions between Lion's Mane and cortisol, emphasizing the importance of evidence-based conclusions.

    Considerations for Individuals

    In the absence of conclusive evidence, individuals should approach the potential impact of Lion's Mane on cortisol levels with caution. It is advisable to monitor personal responses, consult healthcare professionals, and consider factors such as overall health, existing medical conditions, and individual sensitivities.


    While Lion's Mane mushroom has shown promise in various areas of health, including cognitive function, there is currently insufficient evidence to definitively determine its impact on cortisol levels. The lack of specific research on this aspect highlights the need for continued scientific exploration. As individuals consider incorporating Lion's Mane into their regimen, it is crucial to prioritize overall health, consult with healthcare professionals, and stay informed about emerging research in this evolving field.