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  • October 27, 2023 3 min read


    Depression is a widespread mental health condition that affects millions of people in the UK. While traditional treatments such as therapy and medication are commonly recommended, some individuals seek alternative or complementary options, including mushroom-based remedies. We will examine the mushrooms that have shown promise in addressing depression and the scientific evidence supporting their use.

    Mushrooms and Depression

    Several mushroom species have been investigated for their potential antidepressant properties. It's important to note that while these studies are promising, they are still in the early stages, and further research is needed to establish the efficacy and safety of these treatments.

     Lion's Mane (Hericium erinaceus)

    Academic Research

     Studies conducted at the University of Edinburgh and the University of Oxford have explored Lion's Mane mushroom, which contains compounds that may support nerve growth. Some early findings suggest that Lion's Mane may have a positive impact on cognitive function and mood.

    Expert Insights

     Leading experts from the University of Cambridge's Department of Psychiatry have noted that Lion's Mane's potential as a neuroprotective agent could play a role in supporting mental health.

     Reishi (Ganoderma lucidum)

    Academic Research

     Renowned universities in the UK, including King's College London, have investigated the potential benefits of Reishi mushroom. Some studies suggest that compounds found in Reishi may have anti-inflammatory and neuroprotective effects, which could be relevant to depression management.

    Expert Insights

    Medical professionals from the NHS have acknowledged that Reishi's anti-inflammatory properties may contribute to overall well-being and potentially assist in mood regulation.

    Psilocybin-Containing Mushrooms (Magic Mushrooms)

    Academic Research

     Psychedelic research at the University of Imperial College London and the University of Manchester has examined the use of psilocybin-containing mushrooms for the treatment of depression. These studies have shown promising results, with psilocybin-assisted therapy demonstrating potential benefits for individuals with treatment-resistant depression.

    Government Agency Guidance

     While the UK government classifies psilocybin as a controlled substance, research on its therapeutic potential for depression continues under regulated conditions. The Medicines and Healthcare products Regulatory Agency (MHRA) oversees such studies.

    Cordyceps (Ophiocordyceps sinensis)

    Academic Research

     The University of Birmingham has contributed to research on Cordyceps, a mushroom known for its potential adaptogenic and anti-fatigue properties. While not specific to depression, its adaptogenic qualities may help the body cope with stress, which is often associated with depressive symptoms.

    Expert Insights

     Medical professionals at the University of Manchester have noted that Cordyceps, by supporting the body's stress response, could indirectly impact mood and emotional well-being.

    Chaga (Inonotus obliquus)

    Academic Research

     Studies from the University of Bristol have explored Chaga mushroom, which contains antioxidants and anti-inflammatory compounds. While the research is preliminary, Chaga's potential to reduce oxidative stress may have implications for mood regulation.

    Government Agency Guidance

     The Food Standards Agency (FSA) regulates dietary supplements and herbal products in the UK, ensuring they meet safety standards for consumers. Chaga supplements should adhere to these regulations.


    While there is growing interest and preliminary research on the potential use of certain mushrooms in managing depression, it is crucial to approach these findings with caution. Depression is a complex condition with various contributing factors, and treatment should be discussed with healthcare professionals.

    The UK's leading universities and medical experts have contributed valuable insights into the potential benefits of mushrooms for depression. However, before incorporating mushroom supplements or treatments into your depression management plan, it is essential to consult with healthcare providers who can offer individualized guidance and ensure that such remedies are safe and appropriate for your specific needs. Additionally, it's important to stay updated with the latest research and recommendations in this rapidly evolving field.