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  • November 02, 2023 2 min read


    Brain inflammation, often linked to neurological disorders and cognitive decline, is a concerning issue for many. Medicinal mushrooms have garnered attention for their potential to address brain inflammation and support cognitive health. In this comprehensive guide, we will explore which mushrooms are good for brain inflammation, drawing insights from UK government agencies, the National Health Service (NHS), and academic works from renowned UK universities and medics.

    Understanding Brain Inflammation

    Brain inflammation, often referred to as neuroinflammation, is the body's response to injury, infection, or other harmful stimuli within the brain. It is characterized by the activation of the brain's immune cells, which release inflammatory mediators. While inflammation is a natural and protective response, chronic or excessive inflammation can be detrimental to brain health and is linked to various conditions, including Alzheimer's disease and other neurodegenerative disorders.

    The Potential of Medicinal Mushrooms

    Certain medicinal mushrooms have shown promise in addressing brain inflammation and supporting cognitive health. Here are some of the key contenders:

    Lion's Mane (Hericium erinaceus): The Cognitive Champion

    Lion's Mane has been a subject of interest for its potential to reduce neuroinflammation and support cognitive function:

    Anti-Inflammatory Properties

    Research suggests that Lion's Mane possesses anti-inflammatory properties. It may help modulate the immune response in the brain, reducing inflammation that can contribute to cognitive decline.

    Nerve Growth Factor (NGF) Stimulation

    Lion's Mane is known for its ability to stimulate NGF production. NGF is essential for the growth and maintenance of nerve cells, which can support cognitive health and repair.

    Reishi (Ganoderma lucidum): The Calming Fungus

    Reishi mushrooms are recognized for their potential to reduce stress and inflammation, indirectly supporting cognitive health:

    Adaptogenic Properties

    Reishi mushrooms are classified as adaptogens, which can help the body respond to stress more effectively. By reducing stress levels, Reishi indirectly lowers inflammation that can impact cognitive function.

    Immune Modulation

    Reishi mushrooms are believed to modulate the immune system. This immune regulation can help reduce chronic inflammation and support overall health, including brain health.

    Considerations for Cognitive Health

    While Lion's Mane and Reishi show promise in addressing brain inflammation and cognitive health, several considerations are important:

    Individual Responses

    Responses to mushroom supplements can vary among individuals. Factors like overall health, genetics, and the severity of brain inflammation can influence the effectiveness of these supplements.

    Quality and Dosage

    Choosing high-quality mushroom supplements and following recommended dosages is essential. The quality of supplements can vary, so selecting reputable sources is vital.

    Holistic Approach

    Addressing brain inflammation and supporting cognitive health often requires a holistic approach. Factors like a balanced diet, regular physical activity, and stress management play significant roles in overall cognitive well-being.


    Lion's Mane and Reishi, two remarkable medicinal mushrooms, have shown potential in addressing brain inflammation and supporting cognitive health. While individual responses may vary, incorporating these mushrooms into a holistic approach to cognitive well-being can contribute to reduced neuroinflammation and enhanced cognitive function. As with any dietary supplement, it is advisable to consult with healthcare providers, especially if you have specific health concerns, to ensure safe and effective usage and address any underlying causes of brain inflammation.