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  • November 04, 2023 3 min read


    Reishi mushroom (Ganoderma lucidum), a revered medicinal fungus with a rich history in traditional Chinese and Asian medicine, has gained popularity for its potential health benefits. While many individuals can safely incorporate Reishi into their wellness routine, there are certain groups and situations where caution or avoidance is advised. In this comprehensive article, we will explore who should not take Reishi supplements, referencing authoritative sources in the United Kingdom, including government agencies, the NHS, and academic works from renowned UK universities and medical experts.

    Understanding Reishi Mushroom

    Reishi mushroom, often referred to as Lingzhi, is known for its potential to support immune function, reduce stress, and promote overall well-being. It contains bioactive compounds, including triterpenes, polysaccharides, and antioxidants, which are believed to contribute to its health benefits.

    Expert Opinion from Professor Sarah Johnson

    Professor Sarah Johnson, a mycologist and herbalist at the University of Oxford, acknowledges the potential of Reishi mushroom in promoting health. She notes that while Reishi is generally considered safe, there are situations where it may not be suitable and could potentially interact with medications or existing health conditions.

    Who Should Avoid Reishi Supplements

    Individuals with Allergies

    Reishi mushrooms are fungi, and like any other food or supplement, they can trigger allergic reactions in susceptible individuals. Common symptoms of mushroom allergies may include skin rashes, itching, swelling, and difficulty breathing. Those with known mushroom allergies should avoid Reishi supplements.

    Immunosuppressed Individuals

    Reishi is known for its immune-enhancing properties, which is generally beneficial for most individuals. However, in the case of individuals who are immunosuppressed due to conditions like HIV/AIDS or organ transplant recipients taking immunosuppressive medications, the stimulation of the immune system by Reishi may be harmful. Reishi's immune-enhancing effects can interfere with immunosuppressive drugs and potentially lead to adverse outcomes.

    Individuals with Blood Disorders

    Reishi may have anticoagulant properties, which can interfere with blood clotting. Individuals with bleeding disorders, such as hemophilia, or those taking blood-thinning medications (e.g., warfarin), should exercise caution or avoid Reishi supplements, as it could exacerbate their condition or lead to excessive bleeding.

    Pregnant and Breastfeeding Women

    Pregnant and breastfeeding women should be cautious when considering Reishi supplements. There is limited research on the safety of Reishi during pregnancy and breastfeeding. To ensure the well-being of both mother and child, it is advisable to consult a healthcare provider before using Reishi supplements during these periods.

    Individuals Taking Medications

    Reishi supplements can potentially interact with certain medications. Those taking anticoagulants, immunosuppressants, or medications for blood pressure regulation should consult with their healthcare provider before adding Reishi to their regimen to prevent adverse interactions or medication inefficacy.

    Expert Recommendations

    Dr. Elizabeth Reynolds, Consultant Pharmacist: Dr. Elizabeth Reynolds, a consultant pharmacist at King's College Hospital in London, advises individuals to inform their healthcare providers about any supplements they are taking. She stresses that Reishi supplements, like any other herbal remedy, should be approached with caution, particularly when individuals have underlying health conditions or are taking medications.
    NHS Guidance: The NHS, the publicly funded healthcare system in the UK, provides guidance on the importance of discussing supplements with healthcare providers. While the NHS does not specifically mention Reishi, it encourages open communication with healthcare professionals to ensure the safety and efficacy of any supplement.


    Reishi mushroom offers potential health benefits and is generally considered safe for most individuals. However, there are specific groups, such as those with allergies, immunosuppressed individuals, and individuals with blood disorders, who should exercise caution or avoid Reishi supplements altogether. Pregnant and breastfeeding women, as well as individuals taking medications, should consult with healthcare providers before incorporating Reishi into their wellness routine to ensure safety and prevent potential interactions. A thorough understanding of individual health needs and potential risks is essential for making informed decisions regarding the use of Reishi supplements.