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  • October 30, 2023 2 min read


    Lion's Mane mushroom (Hericium erinaceus) is renowned for its cognitive-enhancing properties, but some individuals have reported experiencing fatigue after consumption. In this comprehensive article, we will delve into the research and explore why Lion's Mane may have the unexpected effect of making some people tired. We'll draw on information from UK government agencies, the NHS, and academic works from renowned UK universities and medics to provide a well-informed perspective.

    Lion's Mane Mushroom: An Overview

    The Cognitive Benefits of Lion's Mane

    Lion's Mane mushroom is celebrated for its potential to enhance memory, mental clarity, and focus. Academic research from UK universities has contributed to our understanding of these cognitive benefits.

    The Mystery of Fatigue

    While Lion's Mane is primarily chosen for cognitive enhancement, there have been reports of individuals experiencing fatigue after its consumption. This phenomenon has raised questions about its impact on energy levels.

    Investigating the Potential Causes of Fatigue

    Individual Variability

    One potential reason for Lion's Mane-induced fatigue is individual variability. Not everyone responds to supplements in the same way. The unique biochemistry and physiology of each person can influence how Lion's Mane affects their energy levels.

    Cognitive Overload

    Another consideration is the cognitive-enhancing properties of Lion's Mane. Some individuals may experience mental fatigue due to increased cognitive activity. This heightened mental engagement can lead to a perception of tiredness, especially if consumed in high doses.

    Dosage and Timing

    The dosage and timing of Lion's Mane consumption can play a role in its impact on energy levels. It's essential to follow recommended dosages and, if needed, adjust the timing to align with individual preferences and routines.

    Lack of Scientific Consensus

    While anecdotal reports of Lion's Mane-induced fatigue exist, scientific consensus on this issue is still evolving. More research is needed to understand the mechanisms underlying these effects fully.

    Consultation with Healthcare Professionals

    If you experience fatigue or any unexpected side effects after consuming Lion's Mane, it's advisable to consult with healthcare professionals. They can provide insights and guidance based on your specific circumstances.


    Lion's Mane mushroom is primarily chosen for its cognitive-enhancing properties, but the reported experience of fatigue in some individuals highlights the complexity of how supplements affect different people. The individual variability in responses, potential cognitive overload, and dosage and timing considerations all contribute to the diversity of experiences with Lion's Mane.

    While there is anecdotal evidence of Lion's Mane-induced fatigue, more research is needed to provide a comprehensive understanding of this phenomenon. It's essential for individuals to adjust their Lion's Mane consumption based on their unique responses and to consult with healthcare professionals if they experience any adverse effects.

    The NHS, UK government agencies, and academic research from renowned UK universities and medics emphasize the significance of individual variability and safe usage of supplements to promote overall well-being. Lion's Mane's potential cognitive benefits should be balanced with a consideration of how it may affect energy levels in some individuals.